Article

Electronic Mapping of a Bacterial Genome with Dual Solid-State Nanopores and Active Single-Molecule Control

2021-10-31

Abstract excerpt

We present the first electronic mapping of a bacterial genome using solid-state nanopore technology. A dual-nanopore architecture and active control logic are used to produce single-molecule data that enables estimation of distances between physical tags installed at sequence motifs within double-stranded DNA (dsDNA). Previously developed dual-pore “DNA flossing” control generates multiple scans of tagged regions...

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Literature Corpus work: a7b496c1-70fa-5da6-8c9e-7696dd9de76f
DOI: 10.1101/2021.10.29.466509

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