Article

Targeted nanopore sequencing by real-time mapping of raw electrical signal with UNCALLED

2020-02-03

Abstract excerpt

ReadUntil sequencing allows nanopore devices to selectively eject individual reads from the pore in real-time. This could enable purely computational targeted sequencing, however most mapping methods require basecalling, which is computationally intensive. Here we present UNCALLED ( github.com/skovaka/UNCALLED ), an open-source mapper that rapidly matches streaming nanopore current signals to a reference sequence...

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Literature Corpus work: 1b18f84e-933b-586b-8f09-606f51f945b8
DOI: 10.1101/2020.02.03.931923

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