Article

Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model

2023-08-01

Abstract excerpt

<h4>ABSTRACT</h4> Down syndrome (DS) is characterized by skeletal and brain structural malformations, cognitive impairment, altered hippocampal metabolite concentration and gene expression imbalance. These alterations were usually investigated separately, and the potential rescuing effects of green tea extracts enriched in epigallocatechin-3-gallate (GTE-EGCG) provided disparate results due to different experimen...

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Literature Corpus work: a79ca7e9-c078-57ea-8ac3-07d4cfade818
DOI: 10.1101/2023.07.31.551282

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