Article

Epigallocatechin-3-Gallate Improves Facial Dysmorphology Associated with Down Syndrome

2018-03-05

Abstract excerpt

In Down syndrome (DS), the overall genetic imbalance caused by trisomy of chromosome 21 leads to a complex pleiotropic phenotype that involves a recognizable set of facial traits. Several studies have shown the potential of epigallocatechin-3-gallate (EGCG), a green tea flavanol, as a therapeutic tool for alleviating different developmental alterations associated with DS, such as cognitive impairment, skull dysmor...

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Literature Corpus work: afb0b057-e68c-56dc-8407-e65041d9ab75
DOI: 10.1101/276493

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