Article

Cardiopulmonary structural, functional and immune-alterations in a Down syndrome mouse model and upon modulation of EGCG

2023-03-14

Abstract excerpt

In individuals with Down syndrome (DS), cardiovascular and pulmonary diseases are the most common health problem and result in increased mortality and morbidity. Although these clinical comorbidities are well described, no preclinical models for DS are fully characterized for cardiopulmonary alterations, preventing research to understanding the development and pharmacological modulation of lungs, heart and immune...

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Literature Corpus work: ecc97298-0cfa-574d-8f2b-871b6cabd25d
DOI: 10.1101/2023.03.13.532396

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