Article
Standardized Pipeline for Metabolism and Cognition in GO-DS21 Mouse Model: Investigating Down Syndrome Comorbidities.
Current protocols - 1 Jun 2026
Selloum Mohammed, Silva-Buttkus Patricia da, Riet Fabrice, Dragano Nathalia R V, Garrett Lillian, Jacobs Hugues, Hölter Sabine M, Torquet Nicolas, Rathkolb Birgit, Lindner Loic, Gailus-Durner Valerie, Pavlovic Guillaume, Chan Li, Beckers Johannes, Demoulière Benoit Petit, Fuchs Helmut, Ey Elodie, Sorg Tania, Angelis Martin Hrabe de, Herault Yann
Abstract excerpt
Down syndrome (DS) is the most prevalent form of intellectual disability (ID) globally, with an incidence rate of approximately 1 in 1000 births, affecting over 5 million individuals worldwide. DS is characterized by a genetic profile that predisposes individuals to a range of medical and cognitive conditions, including ID and obesity, which place considerable demands on healthcare systems and families alike....
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