Back to search

Article

Early-life stress impairs development of functional interactions and neuronal activity within prefrontal-amygdala networks <i>in vivo</i>

2024-12-04

Abstract excerpt

Early-life stress (ELS), such as parental neglect or abuse, predisposes an individual to develop mental disorders. Disease hallmarks include heightened amygdala reactivity and impaired prefrontal cortex-amygdala functional interactions, already during childhood and adolescence. However, which cellular and circuit mechanisms underlie these hallmarks, as well as the altered developmental trajectory of prefrontal-amy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a793cee1-9d1f-5421-9345-d547c9badd1c
DOI
10.1101/2024.12.04.626305
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Early-life stress impairs development of functional interactions and neuronal activity within prefrontal-amygdala networks <i>in vivo</i>DOI 10.1101/2024.12.04.626305
From Shortage to Surge: A Developmental Switch in Hippocampal-Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders.Semantic proximity
Chronic unpredictable stress promotes cell-specific plasticity in prefrontal cortex D1 and D2 pyramidal neuronsSemantic proximity
Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivitySemantic proximity
Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J BackgroundSemantic proximity
Early life stress induced sex-specific changes in behavior is paralleled by altered locus coeruleus physiology in BALB/cJ miceSemantic proximity
Amygdala Allostasis and Early Life Adversity: Considering Excitotoxicity and Inescapability in the Sequelae of StressSemantic proximity
Exposure to Prenatal Stress Is Associated With an Excitatory/Inhibitory Imbalance in Rat Prefrontal Cortex and Amygdala and an Increased Risk for Emotional DysregulationSemantic proximity
Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABA-ergic Parvalbumin Interneurons Attenuates Chronic Stress Adaptions in Male MiceSemantic proximity
Maternal Immune Activation Alters Temporal Precision of Spike Generation of CA1 Pyramidal Neurons by Unbalancing GABAergic Inhibition in the OffspringSemantic proximity
Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment.Semantic proximity
Postnatal environmental enrichment enhances memory by shaping hippocampal-prefrontal theta and gamma rhythms in diploid and trisomic female miceSemantic proximity
Maternal separation disrupts noradrenergic control of adult coping behaviorsSemantic proximity
Select a neighboring publication to make it the new centre.