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DNA methylation alterations of <i>PITX2</i> and <i>PANCR</i> are associated with left-right asymmetry of the heart and left ventricle size

2025-08-28

Abstract excerpt

1 <h4>Background</h4> Postmortem genetic testing is a crucial tool to determine the cause of sudden cardiac death and to allow family testing of relatives. While DNA variants are extensively studied in sudden cardiac death, the role of DNA methylation alterations is poorly understood. In contrast to DNA variants, DNA methylation is tissue-specific. Therefore, it is essential to determine the most relevant anatomi...

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Literature Corpus work
a78eed2e-3095-55b7-b7ad-6beac01094b6
DOI
10.1101/2025.08.26.25334499
Open publication

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DNA methylation alterations of <i>PITX2</i> and <i>PANCR</i> are associated with left-right asymmetry of the heart and left ventricle sizeDOI 10.1101/2025.08.26.25334499
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