Article
Differential Methylation in the GSTT1 Regulatory Region in Sudden Unexplained Death and Sudden Unexpected Death in Epilepsy.
International journal of molecular sciences - 10 Mar 2021
Christiansen Steffan Noe, Jacobsen Stine Bøttcher, Andersen Jeppe Dyrberg, Kampmann Marie-Louise, Trudsø Linea Christine, Olsen Kristine Boisen, Tfelt-Hansen Jacob, Banner Jytte, Morling Niels
Abstract excerpt
Sudden cardiac death (SCD) is a diagnostic challenge in forensic medicine. In a relatively large proportion of the SCDs, the deaths remain unexplained after autopsy. This challenge is likely caused by unknown disease mechanisms. Changes in DNA methylation have been associated with several heart diseases, but the role of DNA methylation in SCD is unknown. In this study, we investigated DNA methylation in two SCD...
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