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A deep learning-based multiscale integration of spatial omics with tumor morphology

27 Nov 2025

Abstract excerpt

Spatial Transcriptomics (spTx) offers unprecedented insights into the spatial arrangement of the tumor microenvironment, tumor initiation/progression and identification of new therapeutic target candidates. However, spTx remains unlikely to be routinely used in the near future. Hematoxylin and eosin (H&E) stained histological slides, on the other hand, are routinely generated for a large fraction of cancer...

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PMID: 41310346
DOI: 10.1038/s41467-025-66691-y

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