Article

Immune cell <i>de novo</i> steroidogenesis regulates inflammation resolution and recovery in acute lung injury

2025-09-04

Abstract excerpt

Effective resolution of inflammation following acute lung infection or injury is critical for restoring immune and tissue homeostasis to ensure functional recovery. Prolonged or unresolved inflammation can impair lung repair, promote fibrosis, and contribute to pulmonary dysfunction. While systemic steroid signalling is known to modulate general immune responses, the specific role of immune cell-mediated steroidog...

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Literature Corpus work: 9208e198-5b95-58eb-bd27-b359da44be45
DOI: 10.1101/2025.08.29.673039

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