Article

From GWAS Variant to Function: a Study of ~148,000 Variants for Blood Cell Traits

2021-02-16

Abstract excerpt

Genome-wide association studies (GWAS) have identified hundreds of thousands of genetic variants associated with complex diseases and traits. However, most variants are noncoding and not clearly linked to genes, making it challenging to interpret these GWAS signals. We present a systematic variant-to-function study, prioritizing the most likely functional elements of the genome for experimental follow-up, for >148...

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Literature Corpus work: a76f09c2-7a66-5782-bc5a-342e9eae93e4
DOI: 10.1101/2021.02.16.431409

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