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Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model

2 Oct 2018

Abstract excerpt

Astroglia are the most abundant glia cell in the central nervous system, playing essential roles in maintaining homeostasis. Key functions of astroglia include, but are not limited to, neurotransmitter recycling, ion buffering, immune modulation, neurotrophin secretion, neuronal synaptogenesis and elimination, and blood-brain barrier maintenance. In neurological diseases, it is well appreciated that astroglia...

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PMID: 30398075
DOI: 10.1080/01677063.2018.1513508

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