Article

IW-Scoring: an Integrative Weighted Scoring framework for annotating and prioritizing genetic variations in the noncoding genome

2017-07-15

Abstract excerpt

IW-Scoring represents a new Integrative Weighted Scoring model to annotate and prioritise functionally relevant noncoding variations. The pipeline integrates 11 popular algorithms and outperforms individual methods in three independent data sets, including variants in ClinVar database and GWAS studies, and cancer mutations. Using IW-Scoring, we located 11 recurrently mutated noncoding regions enriched for at least...

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Literature Corpus work: a736858a-a90e-5028-aeb3-0d486356ee24
DOI: 10.1101/163311

Open publication

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