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Article

An Integrative Variant Scoring Function for Finding Novel Genes Associated with Ovarian and Thyroid Cancer.

International journal of environmental research and public health - 26 Mar 2026

Bataycan Amanda, Nurudeen Omodolapo, Mohl Jonathon E, Mitchell Khodeza Begum, Leung Ming-Ying

Abstract excerpt

We devised a quantitative scoring function to assess the cumulative effects of somatic nonsynonymous single-nucleotide variants (SNVs) on protein-coding genes in patients with ovarian cancer (OvCa) and thyroid cancer (ThCa). The goal is to find novel candidate cancer-related genes for downstream bioinformatics analyses and wet-lab studies. With the Genomic Data Commons as primary data resource, SNV information...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42074359
DOI: 10.3390/ijerph23040420
PMCID: PMC13115708

Genes

AHNAK2
CES1
HECTD4
PCDHB4
PLEC
UNC13A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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