Article

A Weights-based variant ranking pipeline for familial complex disorders

2023-08-16

Abstract excerpt

Identifying genetic susceptibility factors for complex disorders remains a challenging task. We have developed a weights-based pipeline to prioritize variants and genes in collections of small and large pedigrees where genetic heterogeneity is likely, but biological commonalities are plausible. The W eights-based v A riant R anking in P edigrees (WARP) pipeline prioritizes variants using 5 weights: disease inc...

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Literature Corpus work: 5ec00c4e-9510-50ef-9cab-d39913b726b0
DOI: 10.1101/2023.08.14.553248

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