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Ultra-low input single tube linked-read library method enables short-read NGS systems to generate highly accurate and economical long-range sequencing information for <i>de novo</i> genome assembly and haplotype phasing

2019-11-29

Abstract excerpt

Long-range sequencing information is required for haplotype phasing, de novo assembly and structural variation detection. Current long-read sequencing technologies can provide valuable long-range information but at a high cost with low accuracy and high DNA input requirement. We have developed a single-tube Transposase Enzyme Linked Long-read Sequencing (TELL-Seq ™ ) technology, which enables a low-cost, high-ac...

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Literature Corpus work
a71d82ea-3e4f-585c-8cea-dab3447fd4fa
DOI
10.1101/852947
Open publication

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