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Article

Epigenetic state determines inflammatory sensing in neuroblastoma

2021-01-28

Abstract excerpt

Immunotherapy has revolutionized cancer treatment, but many cancers are not impacted by currently available immunotherapeutic strategies. Here, we investigated inflammatory signaling pathways in neuroblastoma, a classically “cold” pediatric cancer. By testing the functional response of a panel of 20 diverse neuroblastoma cell lines to three different inflammatory stimuli, we found that all cell lines have intact i...

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Identifiers and source

Literature Corpus work
a719b0ff-7edc-5076-ba0c-db7efb171026
DOI
10.1101/2021.01.27.428523
Open publication

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Epigenetic state determines inflammatory sensing in neuroblastomaDOI 10.1101/2021.01.27.428523
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