Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The immune cell atlas of human neuroblastoma

1 Jun 2022

Abstract excerpt

Understanding the complete immune cell composition of human neuroblastoma (NB) is crucial for the development of immunotherapeutics. Here, we perform single-cell RNA sequencing (scRNA-seq) on 19 human NB samples coupled with multiplex immunohistochemistry, survival analysis, and comparison with normal fetal adrenal gland data. We provide a comprehensive immune cell landscape and characterize cell-state changes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune cells in cancer
Share to Immune Response and Inflammation
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35688160
DOI: 10.1016/j.xcrm.2022.100657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The immune cell atlas of human neuroblastomaPMID 35688160Read ↗

NBAtlas: A harmonized single-cell transcriptomic reference atlas of human neuroblastoma tumorsSemantic proximity Read ↗

A Single-Cell Tumor Immune Atlas for Precision OncologySemantic proximity Read ↗

Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN -Not-Amplified Human NeuroblastomaSemantic proximity Read ↗

The neuroblastoma tumor microenvironment: From an in-depth characterization towards novel therapiesSemantic proximity Read ↗

Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.Semantic proximity Read ↗

MYCN Amplification Is Associated with Repressed Cellular Immunity in Neuroblastoma: An In Silico Immunological Analysis of TARGET DatabaseSemantic proximity Read ↗

Exploration of the molecular characteristics of the tumor–immune interaction and the development of an individualized immune prognostic signature for neuroblastomaSemantic proximity Read ↗

Stratified Immune Profiling Uncovers Prognostic Heterogeneity Beyond MYCN Amplification and Age in NeuroblastomaSemantic proximity Read ↗

Epigenetic state determines inflammatory sensing in neuroblastomaSemantic proximity Read ↗

MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in NeuroblastomaSemantic proximity Read ↗

Predicting tumor immune microenvironment and checkpoint therapy response of head & neck cancer patients from blood immune single-cell transcriptomicsSemantic proximity Read ↗

Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.