Article

Common tandem repeat variants associated with glaucoma risk in individuals of African ancestry

2025-02-21

Abstract excerpt

The contribution of common tandem repeats (TR) variants to common, complex disease remains unknown, especially in populations historically underrepresented in genetic research. We identified common TR variants associated with risk of primary open-angle glaucoma (POAG) in individuals of African ancestry. The POAG-associated TR variants were predominantly found at Alu poly(A) tail elements, regions, retinal developm...

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Literature Corpus work: a710fa7f-6954-5001-889c-ceb04cc14029
DOI: 10.1101/2025.02.19.25322489

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