Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.

doi:10.1016/j.ophtha.2018.10.031

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Article

Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.

Ophthalmology - 1 Jan 2019

Taylor Kent D, Guo Xiuqing, Zangwill Linda M, Liebmann Jeffrey M, Girkin Christopher A, Feldman Robert M, Dubiner Harvey, Hai Yang, Samuels Brian C, Panarelli Joseph F, Mitchell John P, Al-Aswad Lama A, Park Sung Chul, Tello Celso, Cotliar Jeremy, Bansal Rajendra, Sidoti Paul A, Cioffi George A, Blumberg Dana, Ritch Robert, Bell Nicholas P, Blieden Lauren S, Davis Garvin, Medeiros Felipe A, Das Swapan K, Divers Jasmin, Langefeld Carl D, Palmer Nicholette D, Freedman Barry I, Bowden Donald W, Ng Maggie C Y, Ida Chen Yii-Der, Ayyagari Radha, Rotter Jerome I, Weinreb Robert N

Abstract excerpt

PURPOSE: To find genetic contributions to glaucoma in African Americans. DESIGN: Cross-sectional, case-control study. PARTICIPANTS: One thousand eight hundred seventy-five primary open-angle glaucoma (POAG) patients and 1709 controls, self-identified as being of African descent (AD), from the African Descent and Glaucoma Evaluation Study (ADAGES) III and Wake Forest School of Medicine. METHODS: MegaChip genotypes...

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Identifiers

PMID: 30352225
DOI: 10.1016/j.ophtha.2018.10.031
PMCID: PMC6309605

Genes

FNDC3B
AFAP1

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