Article

VASP Promotes Aortic Valve Calcification by Interacting with FBLIM1 to Activate the Focal Adhesion Pathway

2026-07-21

Abstract excerpt

<h4>Background</h4> Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease, yet there is no effective pharmacological therapy to halt or reverse its progression. Focal adhesions (FAs) are dynamic structures that connect cells to the extracellular matrix (ECM), serving not only as mechanical anchors but also as critical signalling hubs that regulate cell adhesion, spreading, migration, d...

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Literature Corpus work: a6c2cde4-8ed4-5008-b805-9111ceb33ba6
DOI: 10.64898/2026.07.17.739282

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