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The Insertion Domain of Mti2 Facilitates the Association of Mitochondrial Initiation Factors with Mitoribosomes in <em>Schizosaccharomyces pombe</em>

2025-04-16

Abstract excerpt

Translation initiation in mitochondria involves unique mechanisms distinct from those in the cytosol or in bacteria. The Schizosaccharomyces pombe mitochondrial translation initiation factor 2 (Mti2) is the ortholog of human MTIF2, which plays a vital role in synthesizing proteins in mitochondria. Here, we investigate the insertion domain of Mti2, which stabilizes its interaction with the ribosome and is crucial f...

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Literature Corpus work
a69950ee-5366-5532-aed0-8842e1038955
DOI
10.20944/preprints202504.1394.v1
Open publication

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The Insertion Domain of Mti2 Facilitates the Association of Mitochondrial Initiation Factors with Mitoribosomes in <em>Schizosaccharomyces pombe</em>DOI 10.20944/preprints202504.1394.v1
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