Article

GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

2023-05-26

Abstract excerpt

Mitochondria contain a multi-copy genome and a distinct set of ribosomes devoted to the exclusive synthesis of proteins that are essential for oxidative phosphorylation. The assembly of mitoribosomes for mitochondrial translation is a poorly understood process. In this study, we identify the uncharacterized GTP-binding protein 8 (GTPBP8) as a mitoribosomal assembly factor that specifically associates with the mito...

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Literature Corpus work: 8d48f3c6-2679-50c7-815c-4dd08158a72e
DOI: 10.1101/2023.05.26.542385

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