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Article

Clear cell carcinomas of the ovary and kidney: clarity through genomics.

The Journal of pathology - 1 Apr 2018

Ji Jennifer X, Wang Yi Kan, Cochrane Dawn R, Huntsman David G

Abstract excerpt

Clear cell ovarian carcinoma (CCOC) and clear cell renal cell carcinoma (ccRCC) both feature clear cytoplasm, owing to the accumulation of cytoplasmic glycogen. Genomic studies have demonstrated several mutational similarities between these two diseases, including frequent alterations in the chromatin remodelling SWI-SNF and cellular proliferation phosphoinositide 3-kinase-mammalian target of rapamycin pathways,...

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Share to Carcinoma, Ovarian Epithelial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29344971
DOI: 10.1002/path.5037

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