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Article

Molecular pathogenesis of ovarian clear cell carcinoma.

Future oncology (London, England) - 1 Jan 2015

Gounaris Ioannis, Brenton James D

Abstract excerpt

Ovarian clear cell carcinoma is a distinct subtype of epithelial ovarian cancer, characterized by an association with endometriosis, glycogen accumulation and resistance to chemotherapy. Key driver events, including ARID1A mutations and HNF1B overexpression, have been recently identified and their functional characterization is ongoing. Additionally, the role of glycogen in promoting the malignant phenotype is...

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Topics

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Share to Adenocarcinoma, Clear Cell
Share to Carcinoma, Ovarian Epithelial
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Gene Expression Regulation, Neoplastic

Share to Neoplasms, Glandular and Epithelial

Share to Nuclear Proteins

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 25952785
DOI: 10.2217/fon.15.45

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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