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Article

Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer

2019-02-01

Abstract excerpt

<h4>ABSTRACT</h4> Transcriptional regulation is highly disease and cell-type specific. We performed H3K27ac chromatin immunoprecipitation and transcriptomic sequencing in primary tumors for the four different subtypes of invasive epithelial ovarian cancer (OC). Histotype-specific regulatory elements (REs) were enriched in enhancers (P<0.001). In silico prediction of putative target genes for histotype-specific R...

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Literature Corpus work
28122f97-79d7-5f93-83ff-1b5fc704417e
DOI
10.1101/537886
Open publication

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Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian CancerDOI 10.1101/537886
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