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Mechanical Centrosome Fracturing during Cell Navigation

2024-10-01

Abstract excerpt

The centrosome is the primary microtubule orchestrator in most eukaryotic cells, nucleating and anchoring microtubules that grow radially and exert forces on cargos. At the same time, mechanical stresses from the microenvironment and cellular shape changes compress and bend microtubules. Yet, centrosomes are membrane-less organelles, raising the question of how centrosomes withstand mechanical forces. Here we disc...

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Literature Corpus work
a62f7c0f-4767-5caa-a361-cb678a39a40c
DOI
10.1101/2024.10.01.615992
Open publication

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Mechanical Centrosome Fracturing during Cell NavigationDOI 10.1101/2024.10.01.615992
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