Article

Progressive mural cell deficiencies across the lifespan in a <i>foxf2</i> model of Cerebral Small Vessel Disease

2025-03-13

Abstract excerpt

Cerebral Small Vessel Disease (SVD) is a leading cause of stroke and dementia and yet is often an incidental finding in aged patients due to the inaccessibility of brain vasculature to imaging. Animal models are important for modelling the development and progression of SVD across the lifespan. In humans, reduced FOXF2 is associated with an increased stroke risk and SVD prevalence in humans. In the zebrafish, fo...

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Literature Corpus work: a5916d2e-9178-529f-afbb-3f40102ce28b
DOI: 10.1101/2025.03.13.643043

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