Article

Predicting evolution using frequency-dependent selection in bacterial populations

2018-09-18

Abstract excerpt

Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae , an important human pathogen, and the pneumococcal conjugate vaccines (PCVs), which target only a fraction of the strains in the population. Here, we use the frequencies of accessory genes to predict changes in the pneumococcal population after vaccination, hypothesizing that these frequ...

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Literature Corpus work: a566ef13-05dd-5319-a398-5df7ace2f8ee
DOI: 10.1101/420315

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