Article

Geographic migration and vaccine-induced fitness changes of <i>Streptococcus pneumoniae</i>

2023-01-18

Abstract excerpt

Streptococcus pneumoniae is a leading cause of pneumonia and meningitis worldwide. Many different serotypes co-circulate endemically in any one location. The extent and mechanisms of spread, and vaccine-driven changes in fitness and antimicrobial resistance (AMR), remain largely unquantified. Using geolocated genome sequences from South Africa (N=6910, 2000-2014) we developed models to reconstruct spread, pairing...

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Literature Corpus work: 942923cb-0fda-58d1-a4d1-fa960505c3a2
DOI: 10.1101/2023.01.18.524577

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