Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders

Abstract excerpt

We characterized the genetic architecture of the attention-deficit hyperactivity disorder-substance use disorder (ADHD-SUD) relationship by investigating genetic correlation, causality, pleiotropy, and common polygenic risk. Summary statistics from genome-wide association studies (GWAS) were used to investigate ADHD (Neff=51,568), cannabis use disorder (CanUD, Neff=161,053), opioid use disorder (OUD,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Attention Deficit Hyperactivity Disorder
• Share to Bipolar Disorder and Treatment
• Share to Substance Abuse Treatment and Outcomes