Article

Clustered transposon insertion via formation of chromatin loops

2022-02-16

Abstract excerpt

Transposons, which are DNA sequences that can move to new positions in the genome, make up a large fraction of eukaryotic genomes and occur in clusters. The insertion of transposons into the genome is hindered by compact folding of chromatin, supposedly preventing aberrant or even pathogenic insertion. Chromatin can, however, be decompacted as a consequence of transposon insertion, leading to increased accessibili...

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Literature Corpus work: a5405db8-e42d-5ce5-bd19-de728f6169e4
DOI: 10.1101/2022.02.16.480760

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