Article

Vascular Heparan Sulfate and Amyloid-β in Alzheimer’s Disease Patients

2024-02-09

Abstract excerpt

Alzheimer’s Disease (AD) is a debilitating neurodegenerative disease characterized by the accumulation of extracellular amyloid-β peptides (Aβ) within the cerebral parenchyma and vasculature, the latter termed cerebral amyloid angiopathy (CAA). This study utilized confocal imaging to investigate heparan sulfate (HS) within the cerebrovasculature and its potential associations with CAA, gender, and ApoE4 genotype....

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Literature Corpus work: f320c620-257c-5a8c-a5af-6c9e18fa7fad
DOI: 10.20944/preprints202402.0567.v1

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