Article
Transcriptional profile of aging in C. elegans.
Current biology : CB - 17 Sept 2002
Lund James, Tedesco Patricia, Duke Kyle, Wang John, Kim Stuart K, Johnson Thomas E
Abstract excerpt
BACKGROUND: Numerous gerontogene mutants leading to dramatic life extensions have been identified in the nematode Caenorhabditis elegans over the last 20 years. Analysis of these mutants has provided a basis for understanding the mechanisms driving the aging process(es). Several distinct mechanisms including an altered rate of aging, increased resistance to stress, decreased metabolic rate, or alterations in a...
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