Article

Manipulation of microbiota reveals altered myelination and white matter plasticity in a model of Huntington disease

2018-09-10

Abstract excerpt

<h4>ABSTRACT</h4> Structural and molecular myelination deficits represent early pathological features of Huntington disease (HD). Recent evidence from germ-free (GF) animals suggests a role for microbiota-gut-brain bidirectional communication in the regulation of myelination. In this study, we aimed to investigate the impact of microbiota on myelin plasticity and oligodendroglial population dynamics in the mixed-...

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Literature Corpus work: a4e5df87-6865-5f49-83af-3d3c7b9900f1
DOI: 10.1101/413112

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