Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Machado Joseph disease severity is linked with gut microbiota alterations in transgenic mice.

Neurobiology of disease - 1 Apr 2023

Gamage Hasinika K A H, Robinson Katherine J, Luu Luan, Paulsen Ian T, Laird Angela S

Abstract excerpt

Emerging evidence suggests the presence of bidirectional interactions between the central nervous system and gut microbiota that may contribute to the pathogenesis of neurodegenerative diseases. However, the potential role of gut microbes in forms of spinocerebellar ataxia, such as the fatal neurodegenerative disease Machado Joseph disease (MJD), remains unexplored. Here, we examined whether gut microbiota...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxin-3
Share to Gastrointestinal Microbiome
Share to Genetic Neurodegenerative Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Machado-Joseph Disease

Share to Mice, Transgenic

Share to Phenotype

Share to Spinocerebellar Ataxias

Source

Identifiers

PMID: 36822548
DOI: 10.1016/j.nbd.2023.106051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Machado Joseph disease severity is linked with gut microbiota alterations in transgenic mice.PMID 36822548Read ↗

Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph diseaseSemantic proximity Read ↗

Effects of Gut Microbiota Alterations on Motor, Gastrointestinal, and Behavioral Phenotype in a Mouse Model of Parkinson's Disease.Semantic proximity Read ↗

Progression and survival of patients with motor neuron disease relative to their fecal microbiotaSemantic proximity Read ↗

Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond.Semantic proximity Read ↗

Gut microbiota, 1013 new pieces in the Parkinson's disease puzzleSemantic proximity Read ↗

Genetic and environmental factors in Alzheimer’s and Parkinson’s diseases and promising therapeutic intervention via fecal microbiota transplantationSemantic proximity Read ↗

Structural changes of gut microbiota in Parkinson’s disease and its correlation with clinical featuresSemantic proximity Read ↗

The contribution of age-related changes in the gut-brain axis to neurological disordersSemantic proximity Read ↗

Gut-Brain Axis and Parkinson's Disease: The Role of Small Intestinal Microbiota from Symptom Onset to Therapeutic PerspectivesSemantic proximity Read ↗

The microbiota-gut-brain axis: An emerging role for the epigenomeSemantic proximity Read ↗

DYT1 mutation alters gut microbiome composition and gut-brain axis dynamics in a mouse modelSemantic proximity Read ↗

Comparative analysis of the gut microbiota composition in the Cln1R151X and Cln2R207X mouse models of Batten disease and in three wild-type mouse strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.