Article

An integrated metagenomics and metabolomics approach implicates the microbiome-gut-brain-axis in the pathogenesis of Huntington’s disease transgenic mice

2020-02-12

Abstract excerpt

<title>Abstract</title> <p>Background: Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder with onset and severity of symptoms influenced by various environmental factors. Recent discoveries have highlighted the importance of the gastrointestinal microbiome in mediating the bidirectional communication between the central and enteric nervous system via circulating factors. Using shotgun s...

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Literature Corpus work: a9df42a5-8a32-5711-a42b-7e3a921919e3
DOI: 10.21203/rs.2.23316/v1

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