Article

Comparative Mutagenesis of SARS-CoV-2 Nonstructural Proteins (NSPs) Across Variants: The Case for RdRp as a Therapeutic Target

2022-10-17

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenicity has been studied extensively from the perspective of structural (S, E, M, N) proteins for purposes in vaccine development. The virus’ nonstructural protein (nsp) components are less characterized, and demonstrate significant potential in efforts to develop novel therapeutic agents. NSP 7, 8, and 12, formed from the cleavage of pp1a and pp1a...

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Literature Corpus work: a4e3bd3a-326e-5d2e-aea2-96a6bf9726f7
DOI: 10.1101/2022.10.15.512346

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