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Article

Emerging genetic diversity of SARS-CoV-2 RNA dependent RNA polymerase (RdRp) alters its B-cell epitopes.

Biologicals : journal of the International Association of Biological Standardization - 1 Jan 2022

Kumar Sushant, Kumari Khushboo, Azad Gajendra Kumar

Abstract excerpt

The RNA dependent RNA polymerase (RdRp) plays crucial role in virus life cycle by replicating the viral genome. The SARS-CoV-2 is an RNA virus that rapidly spread worldwide and acquired mutations. This study was carried out to identify mutations in RdRp as the SARS-CoV-2 spread in India. We compared 50217 RdRp sequences reported from India with the first reported RdRp sequence from Wuhan, China to identify 223...

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Identifiers

PMID: 34802866
DOI: 10.1016/j.biologicals.2021.11.002
PMCID: PMC8595351

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