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Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic <i>Escherichia coli</i>

2018-06-27

Abstract excerpt

Uropathogenic Escherichia coli (UPEC) are the most common etiological agent of uncomplicated urinary tract infection (UTI). An important mechanism of gene regulation in UPEC is phase variation that involves inversion of a promoter-containing DNA element via enzymatic activity of tyrosine recombinases, resulting in biphasic, ON or OFF expression of target genes. The UPEC reference strain CFT073 has five tyrosine s...

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Literature Corpus work
a4e19d4b-928b-58fc-a1fd-7b2e33d28f29
DOI
10.1101/356865
Open publication

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