The streptococcal phase-variable type I restriction modification system SsuCC20p dictates the methylome of Streptococcus suis impacting the transcriptome and virulence in a zebrafish larvae infection model

Abstract excerpt

ABSTRACT Phase-variable type I restriction modification (RM) systems are epigenetic regulatory systems that have been identified in numerous human bacterial pathogens. We previously showed that an emerging zoonotic lineage of Streptococcus suis acquired a phase-variable type I RM system, named SsuCC20p. The SsuCC20p locus was identified in the genome of multiple streptococcal species, indicating that it is not...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Infective Endocarditis Diagnosis and Management
• Share to Neonatal and Maternal Infections