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Article

Decreased expression of type 1 fimbriae by a pst mutant of uropathogenic Escherichia coli reduces urinary tract infection.

Infection and immunity - 1 Aug 2012

Crépin Sébastien, Houle Sébastien, Charbonneau Marie-Ève, Mourez Michaël, Harel Josée, Dozois Charles M

Abstract excerpt

The pstSCAB-phoU operon encodes the phosphate-specific transport system (Pst). Loss of Pst constitutively activates the Pho regulon and decreases bacterial virulence. However, specific mechanisms underlying decreased bacterial virulence through inactivation of Pst are poorly understood. In uropathogenic Escherichia coli (UPEC) strain CFT073, inactivation of pst decreased urinary tract colonization in CBA/J mice....

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Source

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Identifiers

PMID: 22665376
DOI: 10.1128/IAI.00162-12
PMCID: PMC3434566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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