Article

Large-Scale Restructuring of the Caspase-1 Gene Cluster Region in Mammals

2025-06-21

Abstract excerpt

<h4>ABSTRACT</h4> The inflammatory response is an important component of the host immune defence mechanism against pathogens. Activation of the NLRP3 inflammasome has been shown to have a wide range of triggers including fungal, bacterial and viral components, cellular stress and environmental irritants. The NLRP3 inflammasome has been well characterised in mouse and humans but limited information is available fr...

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Literature Corpus work: a4bfa29d-c4b7-5a2f-8a94-3f0b5e07bb3c
DOI: 10.1101/2025.06.19.660630

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