Article

Protective role of mRNA demethylase FTO on axon guiding molecules of nigro-striatal projection system in manganese-induced Parkinsonism

2021-07-19

Abstract excerpt

<title>Abstract</title> <p>Background Parkinson's disease (PD) is a neurodegenerative disease caused by environmental and genetic factors. Manganese (Mn) exposure is a major environmental cause of PD. Cellular and molecular mechanism of Parkinsonism caused by Mn has not been explored clearly. In addition, patients with Mn-induced Parkinsonism show poor therapeutic response to levodopa. Therefore, there is need t...

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Literature Corpus work: a4b9f46e-20d8-5b37-9a8e-0c87df002cc9
DOI: 10.21203/rs.3.rs-710184/v1

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