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Article

Genetic analysis of N6-methyladenosine modification genes in Parkinson's disease.

Neurobiology of aging - 1 Sept 2020

Qin Lixia, Min Shishi, Shu Li, Pan Hongxu, Zhong Junfei, Guo Jifeng, Sun Qiying, Yan Xinxiang, Chen Chao, Tang Beisha, Xu Qian

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disease with a relatively unclear etiology. Previous studies have shown that N6-methyladenosine (m6A) is a vital RNA modification enriched in brain tissue, and that the genes involved in m6A modification are implicated in various neurologic diseases. Here, we conducted a comprehensive genetic analysis using targeted sequencing with molecular inversion probes...

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PMID: 32371107
DOI: 10.1016/j.neurobiolaging.2020.03.018

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