Article
Nutrigenomics in Parkinson's disease: diversity of modulatory actions of polyphenols on epigenetic effects induced by toxins.
Nutritional neuroscience - 1 Jan 2023
Rodrigues-Costa Moara, Fernandes Matheus Santos de Sousa, Jurema-Santos Gabriela Carvalho, Gonçalves Lílian Vanessa da Penha, Andrade-da-Costa Belmira Lara da Silveira
Abstract excerpt
Although the pathogenesis of Parkinson's Disease (PD) is not completely understood, there is a consensus that it can be caused by multifactorial mechanisms involving genetic susceptibility, epigenetic modifications induced by toxins and mitochondrial dysfunction. In the past 20 years, great efforts have been made in order to clarify molecular mechanisms that are risk factors for this disease, as well as to...
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