Article

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

2022-09-06

Abstract excerpt

Medulloblastoma with extensive nodularity (MBEN) are cerebellar tumors with two histologically distinct compartments and varying disease course. In some children MBEN progresses, while others show spontaneous differentiation into more benign tumors. However, the mechanisms that control the tug-of-war between proliferation and differentiation are not well understood. Here, we dissected this process with a multi-mod...

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Literature Corpus work: a4a35259-0312-5b5d-9bdd-6176e6345f8d
DOI: 10.1101/2022.09.02.506321

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