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Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndrome

2024-03-31

Abstract excerpt

Chromosome 22q11.2 deletion is among the strongest known genetic risk factors for neuropsychiatric disorders, including autism and schizophrenia. Brain imaging studies have reported disrupted large-scale functional connectivity in people with 22q11 deletion syndrome (22q11DS). However, the significance and biological determinants of these functional alterations remain unclear. Here, we use a cross-species design t...

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Literature Corpus work
a46c31a3-62e8-5ca0-8085-66cdff1696dd
DOI
10.1101/2024.03.29.587339
Open publication

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Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndromeDOI 10.1101/2024.03.29.587339
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