Article

PI3K in Stemness Regulation: From Development to Cancer

2019-11-15

Abstract excerpt

The PI3K/AKT pathway is a key target in oncology where most efforts are focussed on phenotypes such as cell proliferation and survival. Comparatively little attention has been paid to PI3K in stemness regulation, despite the emerging link between acquisition of stem cell-like features and therapeutic failure in cancer. The aim of this review is to summarise current known and unknowns of PI3K-dependent stemness reg...

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Literature Corpus work: a43959fa-7047-528c-9a49-bf469f7e03c3
DOI: 10.20944/preprints201911.0170.v1

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